Single nucleus RNA-seq data from 128 samples derived from PMDBS samples across Inferior Parietal Lobule (IPL), and Anterior Cingulate Cortex (ACG). Types of Samples: Late stage (Braak 5-6) PD and control post-mortem brains. ASAP Team: Hardy Dataset Name: hardy-pmdbs-sn-rnaseq, v1.1 Principal Investigator: John Hardy Co-Principal Investigator: Mina Ryten; Zane Jaunmuktane Contributors: Fairbrother-Browne, Aine; Brenton, Jonathan; Grant-Peters, Melissa; Reynolds, Regina; Ryten, Mina; Jaunmuktane, Zane Sample Summary: Resources and Additional Information Protocols GitHub: Raw to fastq to mapped: https://github.com/RHReynolds/asap-pd-progression/tree/main; CLustering and QC: https://github.com/mgrantpeters/Hardy_processing_params/tree/main Protocols: https://doi.org/10.17504/protocols.io.yxmvm25xng3p/v1 Dataset DOI: https://doi.org/10.5281/zenodo.16749080 Associated Publications: NA CRN Cloud GitHub: https://github.com/ASAP-CRN CRN Cloud DOI: https://doi.org/10.5281/zenodo.8384742 CRN Cloud Data Dictionary: https://storage.googleapis.com/asap-public-assets/wayfinding/ASAP-CRN-Cloud-Data-Dictionary.pdf Data Dictionary Version: v4.4 CRN Cloud Release Number: v5.0.0 Verily Workbench...
Access requires approval by the data custodian. The collection's description and structure are public; querying the data requires an approved request.
Single-nucleus RNA-seq of human post-mortem brain tissue from Parkinson's disease and control donors is published on ASAP CRN Cloud.