Visium 10x spatial transcriptomic raw data in FASTQ format of the middle temporal gyrus of 96 human subjects. Individuals with incidental Lewy body disease, clinical PD, and healthy control were included. In addition to subject level metadata, Visium spatial metadata such as H&E images and spot coordinates are included. These data are one component of the PD5D cohort, which intends to build a multi-dimensional and multi-omic atlas of PD pathology. For the same subjects, other omics assays have been collected including genotyping, snRNA-seq, and scATAC-seq across two brain tissues: middle temporal gyrus and substantia nigra. ASAP Team: Scherzer Dataset Name: scherzer-pmdbs-spatial-visium-mtg, v1.1 Principal Investigator: Clemens Scherzer Co-Principal Investigator: Xianjun Dong Contributors: Scherzer, Clemens; Dong, Xianjun; Levin, Joshua; Serrano, Geidy; Beach, Thomas; Liao, Zhixiang; Tuncali, Idil; Parker, Jacob; Yuan, Jie; Haywood, Nathan; Simmons, Sean; Adiconis, Xian; Weykopf, Beatrice Sample Summary: Resources and Additional Information Protocols GitHub: https://github.com/TheDongLab/SpatialTranscriptomics Protocols: https://dx.doi.org/10.17504/protocols.io.8epv5k3k6v1b/v1...
Access requires approval by the data custodian. The collection's description and structure are public; querying the data requires an approved request.
PD5D Visium10x spatial transcriptomics is published on ASAP CRN Cloud.