Oral treatment of Thy1-ASO mice with Faecalibacterium prausnitziiA number of microbial taxa have been found to be reduced in Parkinson's disease (PD). Treatment of α-synuclein overexpressing (Thy1-ASO) mice, an animal model of PD, with these taxa has also been shown to improve motor and GI deficits. This dataset focuses on one of the reduced taxa, Faecalibacterium prausnitzii, and the effect of providing it as an oral treatment to both Thy1-ASO mice and wild-type controls. ASAP Team: Sulzer Dataset Name: sulzer-fecal-metagenome-fp-spf, v1.0 Principal Investigator: David Sulzer Co-Principal Investigator: Sarkis Mazmanian Contributors: Moiseyenko, Anastasiya; Mazmanian, Sarkis Sample Summary: Resources and Additional Information Protocols GitHub: https://github.com/seandavi/curatedMetagenomicsNextflow and https://github.com/ASAP-MAC/MazmanianS_MoiseyenkoA/tree/main Protocols: https://dx.doi.org/dx.doi.org/10.17504/protocols.io.e6nvw15dwlmk/v1 Dataset DOI: https://doi.org/10.5281/zenodo.18989559 Associated Publications: https://doi.org/10.1101/2025.09.18.677192 CRN Cloud GitHub: https://github.com/ASAP-CRN CRN Cloud DOI: https://doi.org/10.5281/zenodo.8384742 CRN Cloud Data Dictionary:...Access requires approval by the data custodian. The collection's description and structure are public; querying the data requires an approved request.Oral treatment of Thy1-ASO mice with Faecalibacterium prausnitzii is published on ASAP CRN Cloud.